All Papers

Needham, L.-M.; Saavedra, C.; Rasch, J. K.; Sole-Barber, D.; Schweitzer, B. S.; Fairhall, A. J.; Vollbrecht, C. H.; Wan, S.; Podorova, Y.; Bergsten, A. J.; Mehlenbacher, B.; Zhang, Z.; Tenbrake, L.; Saimi, J.; Kneely, L. C.; Kirkwood, J. S.; Pfeifer, H.; Chapman, E. R.; Goldsmith, R. H. Label-Free Detection and Profiling of Individual Solution-Phase Molecules. Nature 2024. 10.1038/s41586-024-07370-8.

Salij, A. H.; Goldsmith, R. H.; Tempelaar, R. Theory Predicts 2D Chiral Polaritons Based on Achiral Fabry–Pérot Cavities Using Apparent Circular Dichroism. Nat Commun 2024, 15 (1). 10.1038/s41467-023-44523-1.

Chen, T. L.; Salij, A.; Parrish, K. A.; Rasch, J. K.; Zinna, F.; Brown, P. J.; Pescitelli, G.; Urraci, F.; Aronica, L. A.; Dhavamani, A.; Arnold, M. S.; Wasielewski, M. R.; di Bari, L.; Tempelaar, R.; Goldsmith, R. H. A 2D Chiral Microcavity Based on Apparent Circular Dichroism. Nat Commun 2024, 15 (1). 10.1038/s41467-024-47411-4.

Bhadkamkar, A.; Carpenter, S.; Gold, D.; Beede, M.; Goldsmith, R.; van der Weide, D.; Yavuz, D. High-Power Raman Lasing and Efficient Anti-Stokes Generation in Mm-Sized Glass Disk Resonators. Opt Lett 2024. 10.1364/ol.519399.

White, D. S.; Smith, M. A.; Chanda, B.; Goldsmith, R. H. Strategies for Overcoming the Single-Molecule Concentration Barrier. ACS Measurement Science Au 2023, 3, 239–257. 10.1021/acsmeasuresciau.3c00002.

Krasecki, V. K.; Sharma, A.; Cavell, A. C.; Forman, C.; Guo, S. Y.; Jensen, E. T.; Smith, M. A.; Czerwinski, R.; Friederich, P.; Hickman, R. J.; Gianneschi, N.; Aspuru-Guzik, A.; Cronin, L.; Goldsmith, R. H. The Role of Experimental Noise in a Hybrid Classical-Molecular Computer to Solve Combinatorial Optimization Problems. ACS Cent Sci 2023, 9 (7), 1453–1465. 10.1021/acscentsci.3c00515.

Koner, A.; Du, M.; Pannir-Sivajothi, S.; Goldsmith, R. H.; Yuen-Zhou, J. A Path towards Single Molecule Vibrational Strong Coupling in a Fabry-Pérot Microcavity. Chem Sci 2023, 14 (28), 7753–7761. 10.1039/d3sc01411h.

Pan, F.; Karlsson, K.; Nixon, A. G.; Hogan, L. T.; Ward, J. M.; Smith, K. C.; Masiello, D. J.; Nic Chormaic, S.; Goldsmith, R. H. Active Control of Plasmonic-Photonic Interactions in a Microbubble Cavity. Journal of Physical Chemistry C 2022, 126 (48), 20470–20479. 10.1021/acs.jpcc.2c05733.

Gold, D. C.; Bhadkamkar, A. S.; Carpenter, S.; Hogan, L. T.; Dwyer, M.; Beede, M.; Goldsmith, R. H.; van der Weide, D.; Yavuz, D. D. High-Power near-CW Raman Lasing in Mm-Sized Glass Disks. Opt Lett 2022, 47 (16), 4171. 10.1364/ol.465120.

Ying, L.; Mattei, M. S.; Liu, B.; Zhu, S. -Y.; Goldsmith, R. H.; & Yu, Z. Strong and long-range radiative interaction between resonant transitions. Physical Review Research 2022, 4 (1). 10.1103/PhysRevResearch.4.013118

Mazzei Capote, G. A.; Montoya-Ospina, M. C.; Liu, Z.; Mattei, M. S.; Liu, B.; Delgado, A. P.; Yu, Z.; Goldsmith, R. H.; & Osswald, T. A. Compounding a high-permittivity thermoplastic material and its applicability in manufacturing of microwave photonic crystals. Materials 2022, 15 (7), 2492. 10.3390/ma15072492

Mattei, M. S.; Liu, B.; Mazzei Capote, G. A.; Liu, Z; Hacha, B. G.; Osswald, T.; Yu, Z.; Goldsmith, R. H. Three-dimensional printed planar polymer photonic topological insulator waveguides and their robustness to lattice defects. ACS Photonics 2022, 9 (5), 1793-1802. 10.1021/acsphotonics.2c00332

Wang, M. Y.; Thevamaran, M.; Mattei, M. S.; Hacha, B. G.; Mazzei Capote, G. A.; Yu, Z.; Osswald, T.; Goldsmith, R. H.; Thoma, D. J.; Ma, C. Underwater ultrasonic topological waveguides by metal additive manufacturing. Applied Physics Letters 2022, 120, 141702. 10.1063/5.0086951

Ding, J., Wang, F., Pan, F., Yu, P., Gao, N., Goldsmith, R. H., Cai, S., Yang, R., & He, J. (2021). Two-dimensional palladium nanosheet intercalated with gold nanoparticles for plasmon-enhanced electrocatalysis. ACS Catalysis 2021, 11 (21), 13721–13732. 10.1021/acscatal.1c03811

Salij, A.; Goldsmith, R. H.; Tempelaar, R., Theory of Apparent Circular Dichroism Reveals the Origin of Inverted and Noninverted Chiroptical Response under Sample Flipping. Journal of the American Chemical Society 2021, 143 (51), 21519-21531. 10.1021/jacs.1c06752

Xiao, Y. Z.; Yu, Z. N.; Wambold, R. A.; Mei, H. Y.; Hickman, G.; Goldsmith, R. H.; Saffman, M.; Kats, M. A., Efficient generation of optical bottle beams. Nanophotonics 2021, 10 (11), 2893-2901. 10.1515/nanoph-2021-0243

White, D. S.; Chowdhury, S.; Idikuda, V.; Zhang, R. H.; Retterer, S. T.; Goldsmith, R. H.; Chanda, B. cAMP binding to closed pacemaker ion channels is non-cooperative. Nature 2021, 595, 606–610. 10.1038/s41586-021-03686-x

Guo, S. Y.;  Friederich, P.;  Cao, Y. D.;  Wu, T. C.;  Forman, C. J.;  Mendoza, D.;  Degroote, M.;  Cavell, A.;  Krasecki, V.;  Hickman, R. J.;  Sharma, A.;  Cronin, L.;  Gianneschi, N.;  Goldsmith, R. H.; Aspuru-Guzik, A., Perspective A molecular computing approach to solving optimization problems via programmable microdroplet arrays. Matter 2021, 4 (4), 1107-1124. 10.1016/j.matt.2021.03.002

Wasielewski, M. R.; Forbes, M. D. E.; Frank, N. L.; Kowalski, K.; Scholes, G. D.; Yuen-Zhou, J.; Baldo, M. A.; Freedman, D. E.; Goldsmith, R. H.; Goodson, T.; Kirk, M. L.; McCusker, J. K.; Ogilvie, J. P.; Shultz, D. A.; Stoll, S.; Whaley, K. B., Exploiting chemistry and molecular systems for quantum information science. Nature Reviews Chemistry 2020. 10.1038/s41570-020-0200-5

Roch, L. M.; Saikin, S. K.; Hase, F.; Friederich, P.; Goldsmith, R. H.; Leon, S.; Aspuru-Guzik, A., From Absorption Spectra to Charge Transfer in Nanoaggregates of Oligomers with Machine Learning. ACS Nano 2020, 14 (6), 6589-6598. 10.1021/acsnano.0c00384

Alkmin, S.; Brodziski, R.; Simon, H.; Hinton, D.; Goldsmith, R. H.; Patankar, M.; Campagnola, P. J., Role of collagen fiber morphology on ovarian cancer cell migration using image-based models of the extracellular matrix. Cancers 2020, 12 (6). 10.3390/cancers12061390

White, D. S.; Goldschen-Ohm, M. P.; Goldsmith, R. H.; Chanda, B., Top-down machine learning approach for high-throughput single-molecule analysis. Elife 2020, 9. 10.7554/eLife.53357

Cavell, A. C.; Krasecki, V. K.; Li, G. P.; Sharma, A.; Sun, H.; Thompson, M. P.; Forman, C. J.; Guo, S. Y.; Hickman, R. J.; Parrish, K. A.; Aspuru-Guzik, A.; Cronin, L.; Gianneschi, N. C.; Goldsmith, R. H., Optical monitoring of polymerizations in droplets with high temporal dynamic range. Chemical Science 2020, 11 (10), 2647-2656. 10.1039/c9sc05559b

Pan, F.; Smith, K. C.; Nguyen, H. L.; Knapper, K. A.; Masiello, D. J.; Goldsmith, R. H., Elucidating Energy Pathways through Simultaneous Measurement of Absorption and Transmission in a Coupled Plasmonic-Photonic Cavity. Nano Lett 2020, 20 (1), 50-58. 10.1021/acs.nanolett.9b02796

Ying, L.; Zhou, M.; Mattei, M.; Liu, B. Y.; Campagnola, P.; Goldsmith, R. H.; Yu, Z. F., Extended Range of Dipole-Dipole Interactions in Periodically Structured Photonic Media. Phys. Rev. Lett. 2019, 123 (17). 10.1103/PhysRevLett.123.173901

Rea, M. T.; Pan, F.; Horak, E. H.; Knapper, K. A.; Nguyen, H. L.; Vollbrecht, C. H.; Goldsmith, R. H., Investigating the Mechanism of Post-Treatment on PEDOT/PSS via Single-Particle Absorption Spectroscopy. Journal of Physical Chemistry C 2019, 123 (51), 30781-30790. 10.1021/acs.jpcc.9b06259

Hogan, L. T.; Horak, E. H.; Ward, J. M.; Knapper, K. A.; Chormaic, S. N.; Goldsmith, R. H., Toward Real-Time Monitoring and Control of Single Nanoparticle Properties with a Microbubble Resonator Spectrometer. ACS Nano 2019, 13 (11), 12743-12757. 10.1021/acsnano.9b04702

Foote, A. K.; Manger, L. H.; Holden, M. R.; Margittai, M.; Goldsmith, R. H., Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation. Phys. Chem. Chem. Phys 2019, 21 (4), 1863-1871. 10.1039/c8cp06971a

Alkmin, S.; Brodziski, R.; Simon, H.; Hinton, D.; Goldsmith, R. H.; Patankar, M.; Campagnola, P. J., Migration dynamics of ovarian epithelial cells on micro-fabricated image-based models of normal and malignant stroma. Acta Biomaterialia 2019, 100, 92-104. 10.1016/j.actbio.2019.09.037

Wan, C.; Horak, E. H.; King, J.; Salman, J.; Zhang, Z.; Zhou, Y.; Roney, P.; Gundlach, B.; Ramanathan, S.; Goldsmith, R. H.; Kats, M. A., Limiting Optical Diodes Enabled by the Phase Transition of Vanadium Dioxide. ACS Photonics 2018, 5 (7), 2688-2692. 10.1021/acsphotonics.8b00313

Robinson, M. E.; Ng, J. D.; Zhang, H. L.; Buchman, J. T.; Shenderova, O. A.; Haynes, C. L.; Ma, Z. Q.; Goldsmith, R. H.; Hamers, R. J., Optically Detected Magnetic Resonance for Selective Imaging of Diamond Nanoparticles. Anal. Chem. 2018, 90 (1), 769-776. 10.1021/acs.analchem.7b03157

Knapper, K. A.; Pan, F.; Rea, M. T.; Horak, E. H.; Rogers, J. D.; Goldsmith, R. H., Single-particle photothermal imaging via inverted excitation through high-Q all-glass toroidal microresonators. Optics Express 2018, 26 (19), 25020-25030. 10.1364/oe.26.025020

Knapper, K. A.; Horak, E. H.; Vollbrecht, C. H.; Heylman, K. D.; Goldsmith, R. H., Phase-sensitive photothermal imaging of ultrahigh-Q polyoxide toroidal microresonators. Appl. Phys. Lett. 2018, 113 (23). 10.1063/1.5055889

Horak, E. H.; Rea, M. T.; Heylman, K. D.; Gelbwaser-Klimovsky, D.; Saikin, S. K.; Thompson, B. J.; Kohler, D. D.; Knapper, K. A.; Wei, W.; Pan, F.; Gopalan, P.; Wright, J. C.; Aspuru-Guzik, A.; Goldsmith, R. H., Exploring Electronic Structure and Order in Polymers via Single-Particle Microresonator Spectroscopy. Nano Lett 2018, 18 (3), 1600-1607. 10.1021/acs.nanolett.7b04211

Horak, E. H.; Goldsmith, R. H., Drumming up single-molecule beats. Proc. Natl. Acad. Sci. U. S. A. 2018, 115 (44), 11115-11117. 10.1073/pnas.1815764115

Hinton, D. A.; Ng, J. D.; Sun, J.; Lee, S.; Saikin, S. K.; Logsdon, J.; White, D. S.; Marquard, A. N.; Cavell, A. C.; Krasecki, V. K.; Knapper, K. A.; Lupo, K. M.; Wasielewski, M. R.; Aspuru-Guzik, A.; Biteen, J. S.; Gopalan, P.; Goldsmith, R. H., Mapping Forbidden Emission to Structure in Self-Assembled Organic Nanoparticles. J. Am. Chem. Soc. 2018, 140 (46), 15827-15841. 10.1021/jacs.8b09149

Thakkar, N.; Rea, M. T.; Smith, K. C.; Heylman, K. D.; Quillin, S. C.; Knapper, K. A.; Horak, E. H.; Masiello, D. J.; Goldsmith, R. H., Sculpting Fano Resonances To Control Photonic-Plasmonic Hybridization. Nano Lett 2017, 17 (11), 6927-6934. 10.1021/acs.nanolett.7b03332

Padilla, N. A.; Rea, M. T.; Foy, M.; Upadhyay, S. P.; Desrochers, K. A.; Derus, T.; Knapper, K. A.; Hunter, N. H.; Wood, S.; Hinton, D. A.; Cavell, A. C.; Masias, A. G.; Goldsmith, R. H., Tracking Lithium Ions via Widefield Fluorescence Microscopy for Battery Diagnostics. ACS Sensors 2017, 2 (7), 903-908. 10.1021/acssensors.7b00087

Marquard, A. N.; Slaymaker, L. E.; Hamers, R. J.; Goldsmith, R. H., Investigation of activity, stability, and degradation mechanism of surface-supported Pd-PEPPSI complexes for Suzuki-Miyaura coupling. Molecular Catalysis 2017, 429, 10-17. 10.1016/j.molcata.2016.12.001

Manger, L. H.; Rowley, M. B.; Fu, Y. P.; Foote, A. K.; Rea, M. T.; Wood, S. L.; Jin, S.; Wright, J. C.; Goldsmith, R. H., Global Analysis of Perovskite Photophysics Reveals Importance of Geminate Pathways. Journal of Physical Chemistry C 2017, 121 (2), 1062-1071. 10.1021/acs.jpcc.6b11547

Manger, L. H.; Foote, A. K.; Wood, S. L.; Holden, M. R.; Heylman, K. D.; Margittai, M.; Goldsmith, R. H., Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level. Angew. Chem.-Int. Edit 2017, 56 (49), 15584-15588. 10.1002/anie.201708242

Heylman, K. D.; Knapper, K. A.; Horak, E. H.; Rea, M. T.; Vanga, S. K.; Goldsmith, R. H., Optical Microresonators for Sensing and Transduction: A Materials Perspective. Adv. Mater 2017, 29 (30). 10.1002/adma.201700037

Goldschen-Ohm, M. P.; White, D. S.; Klenchin, V. A.; Chanda, B.; Goldsmith, R. H., Observing Single-Molecule Dynamics at Millimolar Concentrations. Angew. Chem.-Int. Edit 2017, 59 (9), 2399-2402. 10.1002/anie.201612050

Fu, Y. P.; Rea, M. T.; Chen, J.; Morrow, D. J.; Hautzinger, M. P.; Zhao, Y. Z.; Pan, D. X.; Manger, L. H.; Wright, J. C.; Goldsmith, R. H.; Jin, S., Selective Stabilization and Photophysical Properties of Metastable Perovskite Polymorphs of CsPbl(3) in Thin Films. Chem. Mat 2017, 29 (19), 8385-8394. 10.1021/acs.chemmater.7b02948

Ng, J. D.; Upadhyay, S. P.; Marquard, A. N.; Lupo, K. M.; Hinton, D. A.; Padilla, N. A.; Bates, D. M.; Goldsmith, R. H., Single-Molecule Investigation of Initiation Dynamics of an Organometallic Catalyst. J. Am. Chem. Soc. 2016, 138 (11), 3876-3883. 10.1021/jacs.6b00357

Lupo, K. M.; Hinton, D. A.; Ng, J. D.; Padilla, N. A.; Goldsmith, R. H., Probing Heterogeneity and Bonding at Silica Surfaces through Single-Molecule Investigation of Base-Mediated Linkage Failure. Langmuir 2016, 32 (36), 9171-9179. 10.1021/acs.langmuir.6b02456

Knapper, K. A.; Heylman, K. D.; Horak, E. H.; Goldsmith, R. H., Chip-scale fabrication of high-Q all-glass toroidal microresonators for single-particle label-free imaging. Adv. Mater 2016, 28 (15), 2945-2950. 10.1002/adma.201504976

Heylman, K. D.; Thakkar, N.; Horak, E. H.; Quillin, S. C.; Cherqui, C.; Knapper, K. A.; Masiello, D. J.; Goldsmith, R. H., Optical microresonators as single-particle absorption spectrometers. Nature Photonics 2016, 10 (12), 788-795. 10.1038/nphoton.2016.217

Goldschen-Ohm, M. P.; Klenchin, V. A.; White, D. S.; Cowgill, J. B.; Cui, Q.; Goldsmith, R. H.; Chanda, B., Structure and dynamics underlying elementary ligand binding events in human pacemaking channels. eLife 2016, 5, e20797. 10.7554/eLife.20797

Gelbwaser-Klimovsky, D.; Saikin, S. K.; Goldsmith, R. H.; Aspuru-Guzik, A., Optical Spectra of p-Doped PEDOT Nanoaggregates Provide Insight into the Material Disorder. ACS Energy Letters 2016, 1, 1100-1105. 10.1021/acsenergylett.6b00443

Dai, J.; Fu, Y. P.; Manger, L. H.; Rea, M. T.; Hwang, L.; Goldsmith, R. H.; Jin, S., Carrier Decay Properties of Mixed Cation Formamidinium-Methylammonium Lead Iodide Perovskite HC(NH2)(2) (1-X) CH3NH3 (x)PbI3 Nanorods. Journal of Physical Chemistry Letters 2016, 7 (24), 5036-5043. 10.1021/acs.jpclett.6b01958

Upadhyay, S. P.; Lupo, K. M.; Marquard, A. N.; Ng, J. D.; Bates, D. M.; Goldsmith, R. H., Fluorescent Dendrimeric Molecular Catalysts Demonstrate Unusual Scaling Behavior at the Single-Molecule Level. Journal of Physical Chemistry C 2015, 119 (34), 19703-19714. 10.1021/acs.jpcc.5b06562

Heylman, K. D.; Knapper, K. A.; Goldsmith, R. H., Photothermal Microscopy of Nonluminescent Single Particles Enabled by Optical Microresonators. Journal of Physical Chemistry Letters 2014, 5 (11), 1917-1923. 10.1021/jz500781g

Heylman, K. D.; Goldsmith, R. H., Photothermal mapping and free-space laser tuning of toroidal optical microcavities. Appl. Phys. Lett. 2013, 103 (21).  10.1063/1.4833539